Natural Product Synthesis via Biocatalysis: An Essay on the Me

Biocatalysis and enzymes in organic synthesis.

[Synthesis and its application to the synthesis of biologically active natural products of new and versatile chiral building blocks].

This article describes a design and synthesis of new and versatile chiral building blocks and its application to the biologically active natural product synthesis. The chiral building blocks were prepared using a biocatalysis in an enantiomerically pure state. As an application of the above chiral building blocks to the synthesis of biologically active natural product, we demonstrated the diast...

Chemical biotechnology: microbial solutions to global change. Editorial overview.

Huimin Zhao is a professor of Chemical and Biomolecular Engineering at the University of Illinois at Urbana-Champaign and the holder of Centennial Chair. His research interests encompass many different aspects of synthetic biology and chemical biology. They include directed evolution and rational design of proteins and pathways, novel approaches for protein, pathway, and genome engineering, the...

Cofactor regeneration – an important aspect of biocatalysis

Biocatalysis has made tremendous advances in the field of synthesis of industrially important products and intermediates. Cofactors are an important part of many enzymes which are involved in biocatalysis. These cofactors are expensive and stoichiometric additions are not economically feasible. This necessitates the in situ cofactor regeneration in biocatalytic processes. Various methods of reg...

Investigation of CO2 and H2O Addition to Natural Gas for Production of Synthesis Gas

General modeling and optimization of syngas production via noncatalytic autothermal partial oxidation of methane are carried out using our developed scientific software which was based on the minimization of total Gibbs energy. In this work, a novel application of the direct search and Newton-Raphson methods was introduced to apply to optimization of a complex chemical reaction. Sensitivity ana...